Treatment response in Paget's disease.
نویسنده
چکیده
منابع مشابه
Chronic treatment of Paget's disease of bone with synthetic human calcitonin.
Twelve patients with Paget's disease of bone were treated with synthetic human calcitonin for seven to 26 months (mean 15.3 months). This group included six patients who had previous therapy. Eleven of the 12 patients experienced relief of the symptoms associated with Paget's disease. The initial therapy of synthetic human calcitonin 0.5-1.0 mg subcutaneously was administered daily until the al...
متن کاملPaget's disease of bone: an endocrine society clinical practice guideline.
OBJECTIVE The aim of this guideline was to formulate practice guidelines for the diagnosis and treatment of Paget's disease of the bone. PARTICIPANTS The guideline was developed by an Endocrine Society-appointed Task Force of experts, a methodologist, and a medical writer. EVIDENCE This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and...
متن کاملTreatment of Paget's disease of bone with single dose intravenous pamidronate.
OBJECTIVES To assess the efficacy of a single intravenous infusion of pamidronate in Paget's disease of bone. METHODS Fourteen patients with active Paget's disease (raised serum alkaline phosphatase, bone pain or neurological involvement) were treated with a single intravenous infusion of 105 mg pamidronate. Patients were assessed for biochemical and clinical improvement for up to two years f...
متن کاملA double-blind, multicentre, placebo-controlled study of tiludronate in Paget's disease of bone.
A multicentre, randomised, placebo-controlled, dose-ranging study was conducted to investigate the therapeutic activity and sustained efficacy of tiludronate (200 mg, 400 mg and 600 mg once daily) taken orally for 12 weeks in patients with Paget's disease. Serum alkaline phosphatase concentrations were compared with baseline at weeks 12 and 24; treatment success was defined as a 50% reduction c...
متن کاملEffectiveness of photodynamic therapy for mammary and extra-mammary Paget's disease: a state of the science review
BACKGROUND Paget's disease is a rare skin disorder occurring in the breast (mammary) or in the groin, genital, peri-anal and axillary regions (extra-mammary). Typical treatment involves surgical excision, which in the case of extra-mammary Paget's disease, can lead to significant morbidity. Photodynamic therapy (PDT) which uses a topical or intravenous photosensitizing agent that is activated b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 54 10 شماره
صفحات -
تاریخ انتشار 1995